DAPTOMYCIN PACKAGE INSERT PDF

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Prescribing Information. View the Prescribing Information for CUBICIN® ( daptomycin for injection) and CUBICIN® RF (daptomycin for injection) below. CUBICIN RF (daptomycin for injection) mg Usage: To reduce the development of drug-resistant bacteria and maintain the effectiveness of CUBICIN and. Package leaflet: Information for the patient. Cubicin® mg powder for solution for injection or infusion daptomycin. Read all of this leaflet carefully before you.

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Cough, eosinophilic pneumonia, organizing pneumonia Nervous system disorders: We do not retain these email addresses. The simulated mean SD steady-state Cmax values were Most adptomycin, these are generic drugs.

Individual plans may vary and formulary information changes. The infusion rate should be maintained at 1. Create Your List of Plans. One subject withdrew from the pacmage after the screening visit, and an additional subject was excluded secondary to a diagnosis of diabetes mellitus. These pacmage are cause for concern given that obesity is considered to be an independent risk factor for morbidity and mortality among surgical and critically ill patients 118 Positive evidence of human fetal risk.

Nausea, vomiting Special senses: Morbid obesity is an independent determinant of death among surgical critically ill patients.

DAPTOMYCIN for Injection Single-Dose Vial mg | Mylan

However, the MDRD equation was derived from patients with renal dysfunction and did not include morbidly obese subjects. Intravenous Infusion over a period of 30 minutes For IV infusion over a period of 30 minutes in adult patients: Antimicrobial therapy should be adjusted as needed based upon test results. Print without Office Info. Where can I find Teva medications?

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Daptomycin for Injection

Either animal studies show no risk but human saptomycin not available or animal studies showed minor risks and human studies done and showed no risk. Consequently, when Dvorchik and Damphouse 11 compared their moderately obese group to the matched nonobese group they compared female subjects only.

The use of high-flux dialysis membranes during 4 hours of hemodialysis may increase the percentage of dose removed compared with low-flux membranes.

Daptomycin exhibits rapid, concentration-dependent bactericidal activity against Gram-positive organisms in vitro. Obesity as an independent risk factor for infectious morbidity in patients who undergo cesarean delivery. Returned for modification 27 April Gently rotate or swirl the vial contents for a few minutes, as needed, to obtain a completely reconstituted solution.

Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection. The following in vitro data are available, but their clinical significance is unknown. Sodium chloride for injection.

Table 4 below provides in-use storage conditions for reconstituted CUBICIN RF in acceptable intravenous diluents in the syringe, vial and intravenous bag for reconstitution and dilution. Ijsert subjects provided signed informed consent prior to inclusion into the study.

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Pediatric Patients 7 to 17 years of Age: Do not use in pregnancy. Home Product Detail print.

In this comparison, the mean C max decreased from Aspirin adptomycin nonsteroidal anti-inflammatory agents such as ibuprofen, naproxen, and ketoprofen were not permitted during the study. The efficacy of daptomycin in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled clinical trials.

Up to 42 days. Tier Description 1 This drug is available at the lowest co-pay.

inxert The protein binding of daptomycin in subjects with moderate hepatic impairment Child-Pugh Class B was similar to that in healthy adult subjects. Indicated for treatment of adults with Staphylococcus aureus bacteremia, including those with right-sided infective endocarditis, caused by methicillin-susceptible and methicillin-resistant isolates. Administration Instructions Parenteral drug products should be inspected visually for particulate matter prior to administration.

Metabolism In in vitro studies, daptomycin was not metabolized by human liver microsomes.

Dosage Modifications Renal impairment: Evidence of our improved control matching standards is further supported by a focused review of previous literature. Interactions with Other Antibiotics In vitro studies have investigated pwckage interactions with other antibiotics.